Get Started
Cancer Genetics & Bioinformatics
Home » Cancer Genetics & Bioinformatics

Training on

Cancer Bioinformatics & Computational Drug Discovery

From Hub Gene Identification to a Journal-Ready Manuscript
Course at a Glance
ENROL NOW
112
About the Course

Cancer research today runs on computation as much as it runs on the bench. Identifying a disease-relevant gene, proving its clinical relevance, and finding a molecule that can act on it now depends on the same pipeline used in leading labs and published in leading journals — public expression databases, network biology, virtual screening, and molecular simulation.

This course walks participants through that entire pipeline, start to finish. It begins with the genetic and molecular basis of cancer, moves through gene expression and hub gene analysis, continues into multi-target computational drug discovery using natural products, and ends with a manuscript formatted and ready for journal submission.

The course is project-centric. From the early classes, every participant (or group) selects a cancer type and dataset, and applies each technique to that project in real time. By Class 20, every participant has been through the full translational research workflow once, hands-on, with their own results to show for it.

Who Should Join

  • BSc (Hons)/MSc students in Biotechnology, Genetic Engineering, Microbiology, Pharmacy, Biochemistry, and related life sciences
  • MPhil/PhD researchers working in cancer biology, molecular biology, or drug discovery
  • University faculty looking to add computational/bioinformatics methods to their research
  • Early-career researchers aiming to publish their first bioinformatics-based paper
  • Anyone with a basic grounding in molecular biology/genetics who wants a structured, applied route into cancer bioinformatics and computational drug discovery


No prior programming or bioinformatics experience is required — the course is built from fundamentals upward.

What You Will Learn

By the end of this course, you will be able to:

  • Explain the genetic and molecular mechanisms driving cancer initiation and progression
  • Retrieve, process, and analyze gene expression data (RNA-Seq and microarray) from public repositories
  • Build a protein–protein interaction network and identify hub genes through enrichment analysis
  • Run survival analysis and generate ROC curves to evaluate the prognostic and diagnostic value of hub genes
  • Carry out pan-cancer expression, mutation, and clinical correlation analysis
  • Analyze tumor immune cell infiltration and its relationship with hub gene expression
  • Identify regulatory miRNAs targeting your hub genes
  • Select and validate multi-drug targets within a chosen pathway
  • Run high-throughput virtual screening of natural product libraries against multiple targets
  • Evaluate ADMET properties, toxicity, and off-target effects of screened candidates
  • Perform molecular dynamics simulation and MM-GBSA binding free energy calculations
  • Write and format a complete manuscript for submission to a peer-reviewed journal

    Course Curriculum

    20 Classes in 4 Modules
    • Module 1 — Cancer Biology & Bioinformatics Foundations (Classes 1–4)
    • Module 2 — Gene Expression & Hub Gene Discovery (Classes 5–11)
    • Module 3 — Multi-Target Drug Discovery (Classes 12–17)
    • Module 4 — Validation & Publication (Classes 18–20)
    ENROL NOW

    Tools & Databases You Will Work With

    Public databases: NCBI, GEO, TCGA, GEPIA2, UALCAN, Kaplan-Meier Plotter, TIMER2.0, cBioPortal, STRING, KEGG, GeneCards

    Expression & network analysis: GEO2R, Cytoscape (CytoHubba, MCODE)

    miRNA analysis: miRDB, TargetScan, miRTarBase

    Docking & virtual screening: AutoDock Vina/QuickVina2, PyRx •

    ADMET & toxicity: SwissADME, ADMETLab, ProTox, pkCSM

    Off-target & selectivity: SwissTargetPrediction, reverse docking

    Molecular dynamics: GROMACS with MM-GBSA binding free energy calculation


    Free and open-source tools and public web servers are prioritized so the course stays accessible; where widely-used commercial alternatives exist, they'll be mentioned alongside.

    Project & Publication Outcome


    Every participant or group carries one research project — one cancer type, one gene/pathway of interest — through the entire pipeline. By Class 20, each project will have produced:

    • A defined, validated set of hub genes with demonstrated prognostic value
    • A shortlisted, ADMET/toxicity-screened multi-target natural product candidate
    • Molecular dynamics-validated binding data (MM-GBSA)
    • A complete manuscript, formatted and referenced for submission to a peer-reviewed journal


    Group projects are welcome and encouraged for larger or more ambitious studies — see the fee waivers below.

    Certification



    Participants who complete the course and their project receive a Certificate of Completion from OMICS Bangladesh.

    FEES Group Discounts

    Group discounts apply per participant when registering together.

    How to Register
    Click
    ENROL NOW
    & and complete the registration form
    Or call 01866-288220 for registration and group-discount queries
    Seats are limited to keep hands-on project mentorship available to every participant/group